Paul was formerly the CEO of OptumLabs since its inception. Before OptumLabs, he served as chief medical officer for Humedica, a next-generation clinical informatics company. He also co-founded and was a leader at Phase Forward and was instrumental in transforming pharmaceutical clinical trials from paper to the web. He has served as a leader in industry organizations such as the National Academy of Medicine's Leadership Consortium for Value and Science-Driven Health Care and the Drug Information Association. Paul holds a B.S. from Rensselaer and an M.D. and Ph.D. from the University of Rochester School of Medicine and Dentistry. He began his career as a physician/investigator and assistant professor at the Massachusetts General Hospital and Harvard Medical School.