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Faculty News and Notes: September 2013
Chris Bystroff, Associate Professor of Biology, was one of the three organizers for the Protein Society Symposium, an international conference which took place in July in Boston. There were 803 attendees.
Joanne S. Luciano and coworkers won Distinguished paper Award at MedInfo2013 held August 20 - 23, 2013 in Copenhagen.
A sizable fraction of patients undergoing drug treatment experiences adverse events or a lack of positive effects. A part of this variability in drug response can be explained by genetic differences between patients the focus of a discipline called pharmacogenetics. This paper investigates how information technologies, ontologies and automated reasoning systems can help establish pharmacogenetics in medical routine and realize the vision of personalized medicine.
Conference: MedInfo 22013 link: http://www.medinfo2013.dk
Reference: About IMIA http://www.imia-medinfo.org/new2/node/1
The International Medical Informatics Association, IMIA organises the internationally acclaimed triennial “World Congress on Medical and Health Informatics” - commonly known as MedInfo.
An RDF/OWL Knowledge Base for Query Answering and Decision Support in Clinical Pharmacogenetics
Matthias Samwald, Robert Freimuth, Joanne S. Luciano, Simon Lin, Robert L. Powers, M. Scott Marshall, Klaus-Peter Adlassnig, Michel Dumontier, Richard D. Boyce
Genetic testing for personalizing pharmacotherapy is bound to become an important part of clinical routine. To address associated issues with data management and quality, we are creating a semantic knowledge base for clinical pharmaco-genetics. The knowledge base is made up of three components: an expressive ontology formalized in the Web Ontology Lan-guage (OWL 2 DL), a Resource Description Framework (RDF) model for capturing detailed results of manual annota-tion of pharmacogenomic information in drug product labels, and an RDF conversion of relevant biomedical datasets. Our work goes beyond the state of the art in that it makes both automated reasoning as well as query answering as simple as possible, and the reasoning capabilities go beyond the capabilities of previously described ontologies.
In June Catherine Royer, Professor of Biological Sciences and Chemistry Constellation Professor - Biocomputation and Bioinformatics at Rensselaer, was invited to speak at the Proteins Gordon Conference in Holderness NH and was voted co-Vice President for the next conference in 2015, along with Vijay Pande from Stanford. We will be co-presidents for the conference to be held in 2017.